FSS Phyto-Biotics Perilla®

With the rising demand for plant stem cell technologies, traditional methods relying on meristematic cells often lack specific activity. FSS Phyto-Biotics Perilla® uses a biotic stress approach, co-culturing Perilla frutescens stem cells with Leuconostoc sp., to induce the production of secondary metabolites. This advanced method enhances the concentration of Rosmarinic Acid, a potent phenolic compound known for its antioxidant, antimicrobial, and anti-inflammatory effects.

Unlike conventional whole-plant extraction, which threatens biodiversity and involves environmentally damaging solvents, this biotechnology provides a sustainable and eco-friendly alternative. Rich in phytoactives, FSS Phyto-Biotics Perilla® supports skin protection, collagen stability, and cellular renewal, making it ideal for anti-aging and soothing cosmetic formulations.

Made Of:

Biotechnologically enhanced Perilla frutescens extract co-cultured with Leuconostoc sp., standardized for Rosmarinic Acid content.

Scientifically Proven

🌱 Rosmarinic Acid Content Assay

Clonal lines of Perilla frutescens co-cultured with Pseudomonas sp. showed a marked increase in Rosmarinic Acid production compared to controls. This confirms biotic stress effectively enhances phytoactive yield for cosmetic use.

🧴 H₂O₂ Protection Test

Rosmarinic Acid at concentrations between 100–130 nM reduced oxidative stress caused by hydrogen peroxide. This demonstrates its ability to neutralize damaging ROS and protect skin cells from oxidative aging.

🌟 ORAC Assay Report

Phyto-Biotics Perilla® showed antioxidant activity comparable to Trolox®, a standard Vitamin E analogue. Results confirmed its antioxidant power is dose dependent, meaning higher concentrations deliver stronger protection against oxidative stress.

🧵 Sirius Red Fast Green Analysis

Phyto-Biotics Perilla® significantly increased collagen synthesis in dermal fibroblasts in a dose-dependent manner. This supports stronger dermal-epidermal junction integrity and improved skin scaffolding for a firmer, more youthful complexion.

🔥 IL-6 ELISA Analysis

When applied to LPS-treated fibroblasts, Phyto-Biotics Perilla® reduced IL-6 production, a key inflammatory marker. This demonstrates powerful anti-inflammatory activity, helping calm skin, reduce fine lines, and counteract aging caused by chronic inflammation.

Solubility

Water-Soluble

Use Levels

1.0%-10.0%

Appearance

Clear to slightly hazy liquid